Heart failure is a condition where the heart is weakened and can’t pump blood as efficiently as it should. This results in symptoms like fatigue and shortness of breath. Some causes of heart failure include coronary artery disease, heart attack, cardiomyopathy, and other conditions that overwork the heart like high blood pressure, diabetes or kidney disease. This condition can be treated with medication and healthy lifestyle changes.
Alzheimer’s disease is a type of dementia that causes problems with memory, thinking, and behavior. The most common early symptom is having difficulty remembering new information. As time goes on, Alzheimer’s worsens and these patients lose ability to respond to their environment. Alzheimer’s is at the forefront of biomedical research today. There is not a cure, but early diagnosis and intervention methods are improving.
In childhood asthma, lungs and airways become easily inflamed when exposed to certain triggers, such as pollen, catching a cold, or a respiratory infection. Symptoms can interfere with daily life even making play difficult. If asthma goes unmanaged it could lead to dangerous asthma attacks. Some symptoms include frequent, intermittent coughing, a whistling or wheezing when exhaling, chest congestion or tightness, chest pain and shortness of breath. Childhood asthma unfortunately has no cure, but with the right treatment symptoms can be controlled.
Crohn’s disease is a chronic inflammatory disease of the digestive tract. Symptoms include diarrhea, stomach pain, nausea, fatigue, constipation, fever, bleeding from rectum and weight loss. These symptoms can occur often and be severe. Treatments for Crohn’s disease include prescription anti-inflammatory medications and over the counter antidiarrhetics as well as lifestyle changes such as a healthy diet and exercise.
Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage on the ends of your bones wears down over time. It can damage any joint in your body. Some symptoms may include pain, tenderness, stiffness, loss of flexibility. These often start slowly and worsen over time. Symptoms can be managed by being active, maintaining a healthy weight, and other treatments, but the underlying process cannot be reversed.
Frailty is a condition associated with aging that has been recognized for centuries. It impairs quality of life for millions of people. Some symptoms may include a general feeling of exhaustion, weakness, cognitive impairment, depression, slow walking and low levels of physical activity. Day to day activities begin to get more and more difficult for these people. There is no cure but symptoms could be managed with diet, supplements, physical activity, etc.
A vaccine is a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. The agent stimulates the body’s immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylactic, or therapeutic.
COVID-19, a disease resulting from SARS-CoV-2 infection, was declared a global pandemic
by the WHO on 11-MAR-2020. Within 4 months of that declaration, there were over
11 million cases of COVID-19 reported globally and over 500 thousand associated deaths
[World health Organization 2020]. With increasing numbers of cases and deaths worldwide, and very limited treatment options, there is an immediate unmet medical need for new effective therapies.